Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR23303753

aa5043c8-a5e7-5acd-948d-6d732e2711b8

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
Male

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V1+0.550
  • PROTEIN_SECRETION+0.520
  • UNFOLDED_PROTEIN_RESPONSE+0.500
  • MTORC1_SIGNALING+0.490
  • OXIDATIVE_PHOSPHORYLATION+0.480
  • E2F_TARGETS+0.350
  • DNA_REPAIR+0.330
  • MYC_TARGETS_V2+0.330
  • G2M_CHECKPOINT+0.300
  • P53_PATHWAY+0.270

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.450
  • KRAS_SIGNALING_DN-0.440
  • INFLAMMATORY_RESPONSE-0.400
  • IL6_JAK_STAT3_SIGNALING-0.380
  • INTERFERON_GAMMA_RESPONSE-0.320
  • APICAL_SURFACE-0.290
  • COMPLEMENT-0.270
  • KRAS_SIGNALING_UP-0.270
  • COAGULATION-0.260
  • PANCREAS_BETA_CELLS-0.260

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

6 twins match this tumor's tissue · 4 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1BS_KSKZ9J7J
brain-umap@2
Embryonal tumors0.930
2BS_G23JJAZY
brain-umap@2
Supratentorial Ependymoma0.915
3BS_G23JJAZY
medullo-epn-umap@date-based
EPNSupratentorial EPN0.885
4R122
bladder-landscape@3
0.884
5MNG449
mng-umap@100
0.878
6EE4F9349-F750-4471-BFE7-7230784569E1
brain-umap@2
0.877
7R143
bladder-landscape@3
0.862
8TCGA-94-7557-01A-11R-2125-07
lung-landscapes@6
cohortMD10.859
9BS_7G42J2SK
brain-umap@2
Supratentorial Ependymoma0.855
10TCGA-21-1075-01A-01R-0692-07
lung-landscapes@6
cohortSQ20.854