Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

MNG294

c6378b89-7bf6-53d4-a60f-bad127cd60af

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MITOTIC_SPINDLE+0.397
  • TGF_BETA_SIGNALING+0.186
  • DNA_REPAIR+0.177
  • G2M_CHECKPOINT+0.151
  • E2F_TARGETS+0.145
  • PI3K_AKT_MTOR_SIGNALING+0.142
  • UV_RESPONSE_DN+0.135
  • PEROXISOME+0.107
  • INTERFERON_ALPHA_RESPONSE+0.072
  • HEME_METABOLISM+0.059

Top 10 suppressed

  • ANGIOGENESIS-0.414
  • TNFA_SIGNALING_VIA_NFKB-0.390
  • MTORC1_SIGNALING-0.370
  • INFLAMMATORY_RESPONSE-0.328
  • PANCREAS_BETA_CELLS-0.325
  • APICAL_SURFACE-0.277
  • MYC_TARGETS_V2-0.250
  • KRAS_SIGNALING_UP-0.230
  • GLYCOLYSIS-0.226
  • ESTROGEN_RESPONSE_LATE-0.196

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG909
mng-umap@100
0.775
2MNG691
mng-umap@100
0.773
3MNG50
mng-umap@100
0.769
4MNG451
mng-umap@100
0.765
5MNG196
mng-umap@100
0.762
6MNG423
mng-umap@100
0.752
7MNG938
mng-umap@100
0.751
8MNG647
mng-umap@100
0.747
9R292
bladder-landscape@3
0.746
10R91
bladder-landscape@3
0.733