Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

TCGA-51-4079-01A-01R-1100-07

· cohortSQ2

c96a08eb-f957-5608-8299-6552074d6398

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
cohortSQ2
subtype
cohortSQ2
age_years
73

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V1+0.570
  • MTORC1_SIGNALING+0.550
  • G2M_CHECKPOINT+0.500
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.480
  • TNFA_SIGNALING_VIA_NFKB+0.480
  • E2F_TARGETS+0.470
  • MYC_TARGETS_V2+0.460
  • CHOLESTEROL_HOMEOSTASIS+0.430
  • HYPOXIA+0.390
  • UNFOLDED_PROTEIN_RESPONSE+0.390

Top 10 suppressed

  • MYOGENESIS-0.030
  • KRAS_SIGNALING_DN+0.030
  • NOTCH_SIGNALING+0.050
  • BILE_ACID_METABOLISM+0.070
  • INTERFERON_ALPHA_RESPONSE+0.080
  • SPERMATOGENESIS+0.080
  • PANCREAS_BETA_CELLS+0.100
  • MITOTIC_SPINDLE+0.110
  • UV_RESPONSE_DN+0.150
  • WNT_BETA_CATENIN_SIGNALING+0.160

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-60-2723-01A-01R-0851-07
lung-landscapes@6
cohortSQ20.944
2R275
bladder-landscape@3
0.929
3SRR13311157
bladder-landscape@3
0.915
4SRR11296801
colon-landscapes@1
0.904
5TCGA-85-8666-01A-11R-2403-07
lung-landscapes@6
cohortSQ10.903
6TCGA-ZF-AA56-01A-31R-A39I-07
bladder-landscape@3
0.901
761496AD6-7265-4D58-87CC-4FEE9723106E
brain-umap@2
0.898
820060039.TNBC
breast-umap@18
C0.898
946061E4B-5256-42AD-BA9A-FBCEBE92B09A
brain-umap@2
0.894
10AA762299-102B-4E35-B4A5-A94A122EF9DB
brain-umap@2
0.892