MNG1175
—
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- —
- cancer_type_detailed
- —
- subtype
- —
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- IL6_JAK_STAT3_SIGNALING+0.559
- TNFA_SIGNALING_VIA_NFKB+0.553
- ALLOGRAFT_REJECTION+0.475
- INFLAMMATORY_RESPONSE+0.467
- TGF_BETA_SIGNALING+0.466
- INTERFERON_GAMMA_RESPONSE+0.443
- KRAS_SIGNALING_UP+0.411
- P53_PATHWAY+0.395
- UV_RESPONSE_DN+0.357
- EPITHELIAL_MESENCHYMAL_TRANSITION+0.354
Top 10 suppressed
- PANCREAS_BETA_CELLS-0.230
- E2F_TARGETS-0.201
- MYC_TARGETS_V2-0.201
- OXIDATIVE_PHOSPHORYLATION-0.197
- KRAS_SIGNALING_DN-0.155
- REACTIVE_OXYGEN_SPECIES_PATHWAY-0.131
- PEROXISOME-0.125
- SPERMATOGENESIS-0.110
- CHOLESTEROL_HOMEOSTASIS-0.097
- BILE_ACID_METABOLISM-0.084
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
6 twins match this tumor's tissue · 4 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | MNG989 | — | — | 0.873 |
| 2 | SRR934741 | — | — | 0.873 |
| 3 | 53933_S131 | — | cohortA1 | 0.870 |
| 4 | BS_VP5Y45Z7 | pilocytic astrocytoma | — | 0.866 |
| 5 | SRR934862 | — | — | 0.865 |
| 6 | MNG464 | — | — | 0.861 |
| 7 | BS_7H4RFCW9 | low-grade glioma | — | 0.857 |
| 8 | R223 | — | — | 0.855 |
| 9 | SJEPD032296_D1.RNA-Seq | EPN | Anaplastic EPN | 0.848 |
| 10 | BS_9HA238XS | Neurofibroma | — | 0.846 |