Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MITOTIC_SPINDLE+0.400
  • G2M_CHECKPOINT+0.300
  • PROTEIN_SECRETION+0.300
  • TGF_BETA_SIGNALING+0.300
  • ANDROGEN_RESPONSE+0.200
  • HEME_METABOLISM+0.200
  • PEROXISOME+0.200
  • UV_RESPONSE_DN+0.200
  • WNT_BETA_CATENIN_SIGNALING+0.200
  • DNA_REPAIR+0.100

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.600
  • IL6_JAK_STAT3_SIGNALING-0.500
  • INFLAMMATORY_RESPONSE-0.500
  • INTERFERON_ALPHA_RESPONSE-0.500
  • INTERFERON_GAMMA_RESPONSE-0.500
  • ANGIOGENESIS-0.400
  • APICAL_SURFACE-0.400
  • COMPLEMENT-0.300
  • HYPOXIA-0.300
  • IL2_STAT5_SIGNALING-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

6 twins match this tumor's tissue · 4 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-0211
medullo-epn-umap@date-based
MedMedulloblastoma0.873
262b39052-bdb9-4ba6-9eb0-f117480c98a8
melanoma-umap@29
0.861
3MDT-AP-3325
medullo-epn-umap@date-based
MedMedulloblastoma0.856
4MDT-AP-0194
medullo-epn-umap@date-based
MedMedulloblastoma0.853
5TCGA-D8-A1XR-01A-11R-A14M-07
breast-umap@18
B0.850
6TCGA-E9-A1R7-01A-11R-A14M-07
breast-umap@18
B0.849
7TCGA-A8-A0AB-01A-11R-A034-07
breast-umap@18
B0.846
8MDT-AP-3311
medullo-epn-umap@date-based
MedMedulloblastoma0.844
9SRR9879265
lung-landscapes@6
cohortMD10.837
10MNG420
mng-umap@100
0.835