Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG920

da715021-f60f-53f2-ad5f-07b1763e4cca

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • TGF_BETA_SIGNALING+0.353
  • MITOTIC_SPINDLE+0.346
  • WNT_BETA_CATENIN_SIGNALING+0.277
  • UV_RESPONSE_DN+0.259
  • E2F_TARGETS+0.238
  • G2M_CHECKPOINT+0.235
  • PROTEIN_SECRETION+0.196
  • NOTCH_SIGNALING+0.188
  • CHOLESTEROL_HOMEOSTASIS+0.165
  • ESTROGEN_RESPONSE_EARLY+0.139

Top 10 suppressed

  • ALLOGRAFT_REJECTION-0.495
  • OXIDATIVE_PHOSPHORYLATION-0.487
  • INFLAMMATORY_RESPONSE-0.410
  • TNFA_SIGNALING_VIA_NFKB-0.381
  • IL6_JAK_STAT3_SIGNALING-0.364
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.351
  • INTERFERON_GAMMA_RESPONSE-0.282
  • MTORC1_SIGNALING-0.277
  • COMPLEMENT-0.272
  • GLYCOLYSIS-0.258

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG522
mng-umap@100
0.823
27C225672-8372-4202-A749-3D8E9A0747CC
brain-umap@2
0.795
3SRR8613768
breast-umap@18
E0.782
4MNG660
mng-umap@100
0.774
5MNG420
mng-umap@100
0.771
6MNG335
mng-umap@100
0.769
774d58c33-0c42-47bc-a55b-f56835480fbe
colon-landscapes@1
0.769
8TCGA-56-8083-01A-11R-2247-07
lung-landscapes@6
cohortMD10.765
9959c268c-637f-4f39-a254-a505c57e8448
melanoma-umap@29
0.759
10SRR934858
brain-umap@2
0.753