MDT-AP-3090
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- overall_survival_months
- 49.08
- os_event
- true
- age_years
- 21
- sex
- M
- new_clusters
- S1
- umap1_2d
- -0.387506721
- umap2_2d
- -10.77915734
- umap1_3d
- -2.517803511
- umap2_3d
- -0.013889555
- umap3_3d
- 6.476529828
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- E2F_TARGETS+0.320
- G2M_CHECKPOINT+0.260
- PROTEIN_SECRETION+0.230
- MYC_TARGETS_V1+0.170
- PANCREAS_BETA_CELLS+0.140
- SPERMATOGENESIS+0.140
- MITOTIC_SPINDLE+0.070
- WNT_BETA_CATENIN_SIGNALING+0.060
- MYC_TARGETS_V2+0.030
- PEROXISOME+0.030
Top 10 suppressed
- TGF_BETA_SIGNALING-0.430
- ANGIOGENESIS-0.420
- CHOLESTEROL_HOMEOSTASIS-0.350
- TNFA_SIGNALING_VIA_NFKB-0.340
- INFLAMMATORY_RESPONSE-0.330
- MYOGENESIS-0.330
- INTERFERON_ALPHA_RESPONSE-0.300
- REACTIVE_OXYGEN_SPECIES_PATHWAY-0.300
- EPITHELIAL_MESENCHYMAL_TRANSITION-0.290
- HYPOXIA-0.280
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
2 twins match this tumor's tissue · 8 come from a different tissue of origin ← cross-tissue dominant
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | BS_M15PW2N0 | medulloblastoma | — | 0.898 |
| 2 | SJEPD031372_D1.RNA-Seq | EPN | Supratentorial EPN | 0.898 |
| 3 | SAMN03290898 | — | — | 0.897 |
| 4 | BS_TE0GVDNG | medulloblastoma | — | 0.891 |
| 5 | SRR975565 | — | — | 0.890 |
| 6 | BS_5PJCHF6V | medulloblastoma | — | 0.889 |
| 7 | BS_A14Z8BBK | medulloblastoma | — | 0.889 |
| 8 | BS_61E80SD6 | medulloblastoma | — | 0.881 |
| 9 | BS_ERWT0ZWE | medulloblastoma | — | 0.880 |
| 10 | BS_HTEPAKCM | medulloblastoma | — | 0.879 |