Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

SRR10842367

fdb75993-624f-54a5-bf2a-0f148967bffd

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.500
  • ANGIOGENESIS+0.400
  • INFLAMMATORY_RESPONSE+0.400
  • APICAL_JUNCTION+0.300
  • COAGULATION+0.300
  • COMPLEMENT+0.300
  • HEDGEHOG_SIGNALING+0.300
  • IL6_JAK_STAT3_SIGNALING+0.300
  • INTERFERON_GAMMA_RESPONSE+0.300
  • MYOGENESIS+0.300

Top 10 suppressed

  • E2F_TARGETS-0.700
  • G2M_CHECKPOINT-0.600
  • MYC_TARGETS_V1-0.500
  • MYC_TARGETS_V2-0.400
  • OXIDATIVE_PHOSPHORYLATION-0.300
  • SPERMATOGENESIS-0.300
  • DNA_REPAIR-0.200
  • MITOTIC_SPINDLE-0.200
  • KRAS_SIGNALING_DN-0.100
  • PANCREAS_BETA_CELLS-0.100

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-FD-A3SQ-01A-21R-A22U-07
bladder-landscape@3
0.878
2TCGA-64-5815-01A-01R-1628-07
lung-landscapes@6
cohortA10.871
3SRR8392884
lung-landscapes@6
cohortA10.867
4ERR2208941
melanoma-umap@29
0.863
5SRR13780273
lung-landscapes@6
cohortMD20.862
6sclc3472_S37.txt
lung-landscapes@6
cohortMD20.861
7SRR6013590
lung-landscapes@6
cohortA10.858
8GSM5359409
bladder-landscape@3
0.858
9BS_ZV9Z3SY6
brain-umap@2
pilocytic astrocytoma0.857
10TCGA-CR-7386-01A-11R-2016-07
head-neck@1
0.848