MDT-AP-2990
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- overall_survival_months
- 24
- os_event
- false
- age_years
- 0.83
- sex
- F
- new_clusters
- S3
- umap1_2d
- -1.790943164
- umap2_2d
- -7.779566527
- umap1_3d
- -2.952157032
- umap2_3d
- -2.489126286
- umap3_3d
- 6.08572712
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- INTERFERON_ALPHA_RESPONSE+0.490
- INTERFERON_GAMMA_RESPONSE+0.450
- TNFA_SIGNALING_VIA_NFKB+0.440
- ALLOGRAFT_REJECTION+0.430
- INFLAMMATORY_RESPONSE+0.430
- COMPLEMENT+0.420
- E2F_TARGETS+0.420
- IL6_JAK_STAT3_SIGNALING+0.410
- G2M_CHECKPOINT+0.390
- IL2_STAT5_SIGNALING+0.340
Top 10 suppressed
- MYC_TARGETS_V2-0.420
- DNA_REPAIR-0.340
- OXIDATIVE_PHOSPHORYLATION-0.240
- PEROXISOME-0.180
- UNFOLDED_PROTEIN_RESPONSE-0.180
- REACTIVE_OXYGEN_SPECIES_PATHWAY-0.160
- HEME_METABOLISM-0.090
- PI3K_AKT_MTOR_SIGNALING-0.070
- MYC_TARGETS_V1-0.060
- TGF_BETA_SIGNALING-0.010
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
9 twins match this tumor's tissue · 1 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | BS_J1AB8PMA | Med | Medulloblastoma | 0.907 |
| 2 | DRR168605 | — | — | 0.906 |
| 3 | SRR8518429 | — | D | 0.898 |
| 4 | MDT-AP-2874 | Med | Medulloblastoma | 0.882 |
| 5 | BS_N4B1SZZH | Med | Medulloblastoma | 0.872 |
| 6 | MDT-AP-2284 | Med | Medulloblastoma | 0.863 |
| 7 | MDT-AP-2167 | Med | Medulloblastoma | 0.855 |
| 8 | SRR934980 | — | — | 0.855 |
| 9 | MDT-AP-2902 | Med | Medulloblastoma | 0.850 |
| 10 | BS_YY5B2XDD | pilocytic astrocytoma | — | 0.850 |