Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0· v2
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Baricitinib

1184c694-91ad-500e-946c-38c71ce42b0d · FDA Approved · targets JAK1, JAK2

Baricitinib

MeasuredReference

Baricitinib targets STK38L_NDR2, JAK1, TYK2.

Primary targets

STK38L_NDR2JAK1TYK2JAK2STK38_NDR1

Top hallmarks

No hallmark data.

Top pathways disrupted

  • pi3k akt mtor signaling6.8k
  • apoptosis5.7k
  • apical junction5.4k

Resistance landscape — Baricitinib

MeasuredReference

1 known oncogenic variants exist on Baricitinib's top targets — see detail for inhibition impact.

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