Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Regorafenib

6e4513c8-27d4-5591-9d16-85e90fbb61b3 · FDA Approved · targets FLT1_VEGFR1, FLT4_VEGFR3, KDR_VEGFR2

Regorafenib

MeasuredReference

Regorafenib targets RAF1, ARAF, RET.

Primary targets

RAF1ARAFRETBRAFHIPK4

Top hallmarks

No hallmark data.

Top pathways disrupted

No pathway data.

Resistance landscape — Regorafenib

MeasuredReference

10 known oncogenic variants exist on Regorafenib's top targets — see detail for inhibition impact.

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