Sorafenib — dose-response

MeasuredDerived

Dose-response curves across the assayed kinome. ← All drugs

Sorafenib × NEK7

MeasuredDerived

IC50

0.71 nM

Hill slope

2.28

R²

0.1169

Top kinases by potency

MeasuredDerived

Ordered by IC50 ascending (fitted).

Kinase	IC50
IKBKB	0.07 nM
BMPR2	0.08 nM
TSSK2	0.09 nM
INSRR	0.14 nM
FER	0.14 nM
MAK	0.16 nM
MARK4	0.16 nM
IRAK4	0.23 nM
BRSK2	0.27 nM
CAMKK1	0.29 nM
CDK1+CCNA2	0.30 nM
MAPK3	0.30 nM
STK4	0.30 nM
PIM2	0.34 nM
PIM3	0.35 nM
MAP3K3	0.38 nM
PRKCB_1	0.55 nM
CSNK1G2	0.58 nM
SGK1	0.62 nM
PRKACB	0.68 nM
NEK7	0.71 nM
TSSK3	0.78 nM
PBK	0.79 nM
PRKCB_2	0.98 nM
RAF1	1.24 nM
DDR2	1.74 nM
BRSK1	1.74 nM
ZAP70	1.80 nM
MAPKAPK2	1.84 nM
PRKCH	1.87 nM