Sorafenib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Sorafenib × SGK1

IC50

0.62 nM

Hill slope

1.62

R²

0.1123

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
IKBKB	0.07 nM
BMPR2	0.08 nM
TSSK2	0.09 nM
INSRR	0.14 nM
FER	0.14 nM
MAK	0.16 nM
MARK4	0.16 nM
IRAK4	0.23 nM
BRSK2	0.27 nM
CAMKK1	0.29 nM
CDK1+CCNA2	0.30 nM
MAPK3	0.30 nM
STK4	0.30 nM
PIM2	0.34 nM
PIM3	0.35 nM
MAP3K3	0.38 nM
PRKCB_1	0.55 nM
CSNK1G2	0.58 nM
SGK1	0.62 nM
PRKACB	0.68 nM
NEK7	0.71 nM
TSSK3	0.78 nM
PBK	0.79 nM
PRKCB_2	0.98 nM
RAF1	1.24 nM
DDR2	1.74 nM
BRSK1	1.74 nM
ZAP70	1.80 nM
MAPKAPK2	1.84 nM
PRKCH	1.87 nM