Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

EPT0521

EPN · Posterior Fossa EPN

130bb0af-f9d0-57d2-b717-a8af31ecd864

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
EPN
cancer_type_detailed
subtype
Posterior Fossa EPN
cancer_type
EPN
subtype
Posterior Fossa EPN
e1_e2
E2
umap1_2d
-5.540894529
umap2_2d
0.284603131
umap1_3d
-0.272986655
umap2_3d
3.295786765
umap3_3d
-0.184897954
dataset
EPN-Toronto

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.470
  • NOTCH_SIGNALING+0.340
  • WNT_BETA_CATENIN_SIGNALING+0.330
  • INTERFERON_GAMMA_RESPONSE+0.280
  • MITOTIC_SPINDLE+0.250
  • FATTY_ACID_METABOLISM+0.240
  • HEME_METABOLISM+0.180
  • CHOLESTEROL_HOMEOSTASIS+0.170
  • MYC_TARGETS_V2+0.140
  • MYOGENESIS+0.140

Top 10 suppressed

  • PANCREAS_BETA_CELLS-0.370
  • TNFA_SIGNALING_VIA_NFKB-0.290
  • INFLAMMATORY_RESPONSE-0.260
  • MTORC1_SIGNALING-0.250
  • MYC_TARGETS_V1-0.240
  • KRAS_SIGNALING_UP-0.230
  • ANGIOGENESIS-0.220
  • IL2_STAT5_SIGNALING-0.220
  • ALLOGRAFT_REJECTION-0.180
  • HYPOXIA-0.170

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
149718_S125
lung-landscapes@6
cohortA10.635
2SRR8942967
bladder-landscape@3
0.628
35547236E-885B-4CE8-B733-9D2E2D60941C
brain-umap@2
0.627
4TCGA-E2-A10B-01A-11R-A10J-07
breast-umap@18
B0.604
5MBCproject_6016_T1_RNA
breast-umap@18
A0.596
6MNG671
mng-umap@100
0.594
7SRR6013601
lung-landscapes@6
cohortA10.582
8MNG294
mng-umap@100
0.579
9MNG1086
mng-umap@100
0.577
10MNG909
mng-umap@100
0.575