s_150324_3b
EPN · Posterior Fossa EPN
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- EPN
- cancer_type_detailed
- —
- subtype
- Posterior Fossa EPN
- cancer_type
- EPN
- subtype
- Posterior Fossa EPN
- e1_e2
- E2
- umap1_2d
- -6.992956538
- umap2_2d
- 1.659945256
- umap1_3d
- 0.064336546
- umap2_3d
- 4.737734375
- umap3_3d
- 0.154447254
- dataset
- EPN-Heidelberg
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- G2M_CHECKPOINT+0.210
- MITOTIC_SPINDLE+0.200
- E2F_TARGETS+0.180
- DNA_REPAIR+0.070
- MYC_TARGETS_V1+0.070
- SPERMATOGENESIS+0.040
- PROTEIN_SECRETION+0.030
- MYC_TARGETS_V2-0.010
- HEME_METABOLISM-0.060
- UV_RESPONSE_DN-0.070
Top 10 suppressed
- IL6_JAK_STAT3_SIGNALING-0.600
- TNFA_SIGNALING_VIA_NFKB-0.580
- ANGIOGENESIS-0.570
- INFLAMMATORY_RESPONSE-0.530
- HYPOXIA-0.510
- INTERFERON_ALPHA_RESPONSE-0.510
- EPITHELIAL_MESENCHYMAL_TRANSITION-0.480
- COAGULATION-0.470
- COMPLEMENT-0.470
- INTERFERON_GAMMA_RESPONSE-0.470
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
4 twins match this tumor's tissue · 6 come from a different tissue of origin ← cross-tissue dominant
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | BS_2SFTWNVE | medulloblastoma | — | 0.948 |
| 2 | BS_5PJCHF6V | medulloblastoma | — | 0.947 |
| 3 | BS_HTEPAKCM | medulloblastoma | — | 0.947 |
| 4 | SRR10900006 | — | — | 0.947 |
| 5 | SJEPD031175_D1.RNA-Seq | EPN | Posterior Fossa EPN | 0.944 |
| 6 | SRR655864 | GTEX | — | 0.941 |
| 7 | TCGA-21-1082-01A-01R-A96U-41 | — | cohortSQ1 | 0.937 |
| 8 | BS_3NWQXPQV | medulloblastoma | — | 0.936 |
| 9 | SJEPD030097_D2.RNA-Seq | EPN | Spinal EPN | 0.935 |
| 10 | BS_QRDT19KS | medulloblastoma | — | 0.933 |