Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG742

2e5d366e-a715-588d-b714-290278b908a5

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.690
  • INTERFERON_GAMMA_RESPONSE+0.566
  • TNFA_SIGNALING_VIA_NFKB+0.486
  • MYC_TARGETS_V2+0.462
  • OXIDATIVE_PHOSPHORYLATION+0.453
  • MYC_TARGETS_V1+0.437
  • IL6_JAK_STAT3_SIGNALING+0.432
  • INFLAMMATORY_RESPONSE+0.426
  • MTORC1_SIGNALING+0.406
  • ALLOGRAFT_REJECTION+0.362

Top 10 suppressed

  • WNT_BETA_CATENIN_SIGNALING-0.312
  • BILE_ACID_METABOLISM-0.280
  • MITOTIC_SPINDLE-0.156
  • NOTCH_SIGNALING-0.134
  • UV_RESPONSE_DN-0.106
  • MYOGENESIS-0.093
  • PEROXISOME-0.071
  • XENOBIOTIC_METABOLISM-0.039
  • CHOLESTEROL_HOMEOSTASIS-0.031
  • TGF_BETA_SIGNALING-0.029

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1R261
bladder-landscape@3
0.896
2TCGA-GC-A6I1-01A-12R-A31N-07
bladder-landscape@3
0.885
3TCGA-37-3792-01A-01R-0980-07
lung-landscapes@6
cohortA10.884
4TCGA-DK-A3WW-01A-22R-A23N-07
bladder-landscape@3
0.880
5TCGA-BT-A42F-01A-11R-A23W-07
bladder-landscape@3
0.875
6TCGA-33-4566-01A-01R-1443-07
lung-landscapes@6
cohortA10.873
7TCGA-CN-A49B-01A-31R-A24H-07
head-neck@1
0.872
8TCGA-ZF-A9RD-01A-11R-A42T-07
bladder-landscape@3
0.870
9TCGA-22-0940-01A-01R-0692-07
lung-landscapes@6
cohortSQ10.861
10SRR8518246
breast-umap@18
C0.858