MDT-AP-3326
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- age_years
- 10.7
- sex
- F
- new_clusters
- C5
- umap1_2d
- 2.579893463
- umap2_2d
- 4.366000357
- umap1_3d
- 1.631196027
- umap2_3d
- -0.860711684
- umap3_3d
- -2.487898574
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- PANCREAS_BETA_CELLS+0.270
- KRAS_SIGNALING_DN+0.220
- PROTEIN_SECRETION+0.210
- KRAS_SIGNALING_UP+0.180
- SPERMATOGENESIS+0.170
- HEDGEHOG_SIGNALING+0.150
- INTERFERON_ALPHA_RESPONSE+0.140
- ESTROGEN_RESPONSE_EARLY+0.110
- INTERFERON_GAMMA_RESPONSE+0.100
- ANDROGEN_RESPONSE+0.050
Top 10 suppressed
- MYC_TARGETS_V1-0.580
- E2F_TARGETS-0.550
- DNA_REPAIR-0.510
- G2M_CHECKPOINT-0.510
- OXIDATIVE_PHOSPHORYLATION-0.470
- MYC_TARGETS_V2-0.440
- UNFOLDED_PROTEIN_RESPONSE-0.360
- MITOTIC_SPINDLE-0.270
- EPITHELIAL_MESENCHYMAL_TRANSITION-0.260
- ADIPOGENESIS-0.240
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
6 twins match this tumor's tissue · 4 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | BS_A14Z8BBK | Med | Medulloblastoma | 0.870 |
| 2 | MDT-AP-0810 | Med | Medulloblastoma | 0.848 |
| 3 | BS_SFKZSJN1 | low-grade glioma | — | 0.847 |
| 4 | MDT-AP-0305 | Med | Medulloblastoma | 0.846 |
| 5 | BS_5PEFNDCY | Glial-neuronal tumor NOS | — | 0.838 |
| 6 | MDT-AP-2913 | Med | Medulloblastoma | 0.835 |
| 7 | BS_2SFTWNVE | Med | Medulloblastoma | 0.834 |
| 8 | BS_B1HVNV0T | ATRT | — | 0.833 |
| 9 | SRR659602 | GTEX | — | 0.832 |
| 10 | C3N-03057 | — | cohortA1 | 0.823 |