Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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7478db87-0751-4771-941f-9fccdf01853d

3b883f88-71e6-5e08-b1b7-23b7c582c773

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.500
  • G2M_CHECKPOINT+0.400
  • MITOTIC_SPINDLE+0.400
  • ANGIOGENESIS+0.300
  • MYC_TARGETS_V1+0.300
  • WNT_BETA_CATENIN_SIGNALING+0.300
  • MYC_TARGETS_V2+0.200
  • NOTCH_SIGNALING+0.200
  • UV_RESPONSE_DN+0.200
  • APICAL_SURFACE+0.100

Top 10 suppressed

  • INTERFERON_GAMMA_RESPONSE-0.600
  • ALLOGRAFT_REJECTION-0.500
  • INTERFERON_ALPHA_RESPONSE-0.500
  • TNFA_SIGNALING_VIA_NFKB-0.500
  • COMPLEMENT-0.400
  • INFLAMMATORY_RESPONSE-0.400
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.400
  • APOPTOSIS-0.300
  • COAGULATION-0.300
  • ESTROGEN_RESPONSE_EARLY-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1ec882950-7595-4ab7-a8b8-86d1422a948a
melanoma-umap@29
0.878
2C3N-02435
lung-landscapes@6
cohortSQ10.862
3TCGA-56-8083-01A-11R-2247-07
lung-landscapes@6
cohortMD10.862
4SRR8392888
lung-landscapes@6
cohortMD10.859
5SRR2932838
head-neck@1
0.857
6b0be4742-ccb7-48e2-b756-0c384321114e
melanoma-umap@29
0.855
7TCGA-63-A5MW-01A-11R-A26W-07
lung-landscapes@6
cohortMD10.854
8BS_44A3ES23
brain-umap@2
medulloblastoma0.852
9SRR6013547
lung-landscapes@6
cohortMD10.852
10SAMN03290896
melanoma-umap@29
0.849