Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR12202486

3d9f93bf-7479-592a-a06a-5ee9db95c339

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INTERFERON_ALPHA_RESPONSE+0.680
  • INTERFERON_GAMMA_RESPONSE+0.610
  • ALLOGRAFT_REJECTION+0.580
  • IL6_JAK_STAT3_SIGNALING+0.440
  • INFLAMMATORY_RESPONSE+0.410
  • COMPLEMENT+0.300
  • PANCREAS_BETA_CELLS+0.230
  • HEDGEHOG_SIGNALING+0.210
  • IL2_STAT5_SIGNALING+0.210
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.190

Top 10 suppressed

  • E2F_TARGETS-0.580
  • MYC_TARGETS_V2-0.560
  • MYC_TARGETS_V1-0.550
  • G2M_CHECKPOINT-0.530
  • OXIDATIVE_PHOSPHORYLATION-0.500
  • GLYCOLYSIS-0.410
  • ADIPOGENESIS-0.400
  • MTORC1_SIGNALING-0.390
  • CHOLESTEROL_HOMEOSTASIS-0.360
  • DNA_REPAIR-0.350

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR8942969
bladder-landscape@3
0.953
2TCGA-86-8671-01A-11R-2403-07
lung-landscapes@6
cohortMD20.925
3SRR12202445
bladder-landscape@3
0.922
4SRR8518166
breast-umap@18
D0.922
5C3N-00433
lung-landscapes@6
cohortMD20.915
646a6f49d-2ab8-41fb-ba8c-951a160e5d08
colon-landscapes@1
0.912
7DRR168543
bladder-landscape@3
0.912
8MNG64
mng-umap@100
0.911
9TCGA-22-1005-01A-01R-0692-07
lung-landscapes@6
cohortMD20.910
10TCGA-AQ-A7U7-01A-22R-A352-07
breast-umap@18
D0.910