Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR5088891

645b413f-13c5-5e05-91c4-41317db3e7a9

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.500
  • ALLOGRAFT_REJECTION+0.400
  • G2M_CHECKPOINT+0.400
  • INTERFERON_ALPHA_RESPONSE+0.400
  • INTERFERON_GAMMA_RESPONSE+0.400
  • MYC_TARGETS_V1+0.400
  • MYC_TARGETS_V2+0.400
  • DNA_REPAIR+0.200
  • IL2_STAT5_SIGNALING+0.200
  • MITOTIC_SPINDLE+0.200

Top 10 suppressed

  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.400
  • ANGIOGENESIS-0.300
  • CHOLESTEROL_HOMEOSTASIS-0.300
  • COAGULATION-0.300
  • HYPOXIA-0.300
  • MYOGENESIS-0.300
  • NOTCH_SIGNALING-0.300
  • FATTY_ACID_METABOLISM-0.200
  • PANCREAS_BETA_CELLS-0.200
  • PEROXISOME-0.200

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1c2d0d36b-83b0-4a2b-a5d7-6567bf5aa557
melanoma-umap@29
0.863
2TCGA-E2-A1II-01A-11R-A144-07
breast-umap@18
E0.853
3TCGA-CN-A499-01A-11R-A24H-07
head-neck@1
0.846
4TCGA-BH-A1FC-01A-11R-A13Q-07
breast-umap@18
E0.844
5SRR1313144
breast-umap@18
D0.837
69eec558d-cc8f-4816-80a5-b6aac4cbb94e
melanoma-umap@29
0.832
7KG1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
ccle-aml@v2024.1
AML0.826
883a1d91a-3e74-4106-96d1-eec558404c29
colon-landscapes@1
0.821
9MBCproject_0095_T3_RNA
breast-umap@18
E0.820
1020100125.TNBC
breast-umap@18
E0.815