Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

TCGA-GM-A2DC-01A-11R-A18M-07

· B

791d7e55-6fcb-5563-a6cf-8fdb3ed068d4

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
B
subtype
B
overall_survival_months
84
os_event
false

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • OXIDATIVE_PHOSPHORYLATION+0.300
  • BILE_ACID_METABOLISM+0.270
  • DNA_REPAIR+0.230
  • ADIPOGENESIS+0.190
  • PEROXISOME+0.160
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.130
  • MYC_TARGETS_V2+0.100
  • PANCREAS_BETA_CELLS+0.060
  • HEME_METABOLISM+0.010
  • MYOGENESIS+0.010

Top 10 suppressed

  • E2F_TARGETS-0.560
  • G2M_CHECKPOINT-0.560
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.480
  • INTERFERON_ALPHA_RESPONSE-0.480
  • INFLAMMATORY_RESPONSE-0.470
  • INTERFERON_GAMMA_RESPONSE-0.450
  • MITOTIC_SPINDLE-0.410
  • ALLOGRAFT_REJECTION-0.340
  • HEDGEHOG_SIGNALING-0.340
  • IL2_STAT5_SIGNALING-0.330

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-LL-A6FP-01A-11R-A31O-07
breast-umap@18
B0.913
2TCGA-CF-A5U8-01A-11R-A28M-07
bladder-landscape@3
0.894
3TCGA-55-6972-01A-11R-1949-07
lung-landscapes@6
cohortA20.886
4TCGA-BH-A0HN-01A-11R-A10U-07
breast-umap@18
B0.880
5BS_V9HVBBDW
medullo-epn-umap@date-based
MedMedulloblastoma0.870
6TCGA-CF-A47W-01A-11R-A23W-07
bladder-landscape@3
0.868
7SRR2016961
head-neck@1
0.859
8MNG1050
mng-umap@100
0.857
9cf2834ac-00ed-4372-be25-042f38241196
melanoma-umap@29
0.855
10TCGA-AO-A12H-01A-11R-A115-07
breast-umap@18
B0.854