Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR2016961

1dea0b5e-9ffc-53f9-a7d6-8cd3f46e1860

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
male

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • OXIDATIVE_PHOSPHORYLATION+0.310
  • PANCREAS_BETA_CELLS+0.290
  • BILE_ACID_METABOLISM+0.120
  • FATTY_ACID_METABOLISM+0.120
  • HEME_METABOLISM+0.100
  • P53_PATHWAY+0.100
  • PEROXISOME+0.100
  • ADIPOGENESIS+0.060
  • WNT_BETA_CATENIN_SIGNALING+0.000
  • XENOBIOTIC_METABOLISM-0.020

Top 10 suppressed

  • E2F_TARGETS-0.590
  • G2M_CHECKPOINT-0.520
  • ALLOGRAFT_REJECTION-0.460
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.450
  • MITOTIC_SPINDLE-0.440
  • IL6_JAK_STAT3_SIGNALING-0.420
  • INTERFERON_ALPHA_RESPONSE-0.400
  • MYC_TARGETS_V2-0.400
  • INTERFERON_GAMMA_RESPONSE-0.390
  • HEDGEHOG_SIGNALING-0.380

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR12202450
bladder-landscape@3
0.911
2TCGA-CF-A5U8-01A-11R-A28M-07
bladder-landscape@3
0.906
3C3L-03721
lung-landscapes@6
cohortA20.896
41d0437fc-c8ad-47be-822d-b95ad10f0e4a
colon-landscapes@1
0.891
5TCGA-MP-A5C7-01A-11R-A262-07
lung-landscapes@6
cohortA20.886
6MDT-AP-0349
medullo-epn-umap@date-based
MedMedulloblastoma0.877
7SRR4296076
lung-landscapes@6
cohortA10.873
8TCGA-37-4129-01A-01R-1100-07
lung-landscapes@6
cohortSC0.873
9TCGA-E2-A1B4-01A-11R-A12P-07
breast-umap@18
B0.872
10SRR975556
colon-landscapes@1
0.867