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MDT-AP-0597

Med · Medulloblastoma

88dfc171-9701-5653-b2ca-4f5772315ce8

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
overall_survival_months
51
os_event
false
age_years
5
sex
M
new_clusters
C6
umap1_2d
3.355455589
umap2_2d
7.187319147
umap1_3d
2.323122792
umap2_3d
-1.389945163
umap3_3d
-4.704739563
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.580
  • G2M_CHECKPOINT+0.530
  • MITOTIC_SPINDLE+0.480
  • DNA_REPAIR+0.390
  • PROTEIN_SECRETION+0.260
  • HEME_METABOLISM+0.250
  • PI3K_AKT_MTOR_SIGNALING+0.250
  • UNFOLDED_PROTEIN_RESPONSE+0.220
  • TGF_BETA_SIGNALING+0.160
  • ADIPOGENESIS+0.140

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.390
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.360
  • INTERFERON_GAMMA_RESPONSE-0.330
  • KRAS_SIGNALING_DN-0.290
  • PANCREAS_BETA_CELLS-0.290
  • COAGULATION-0.280
  • KRAS_SIGNALING_UP-0.280
  • ALLOGRAFT_REJECTION-0.240
  • MYOGENESIS-0.230
  • INFLAMMATORY_RESPONSE-0.200

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1TCGA-56-8082-01A-11R-2247-07
lung-landscapes@6
cohortSQ10.811
2MDT-AP-3307
medullo-epn-umap@date-based
MedMedulloblastoma0.805
3TCGA-AQ-A04H-01B-11R-A10J-07
breast-umap@18
B0.802
407463FB6-787C-4FAC-8954-C694EEF27F69
brain-umap@2
0.792
5TCGA-22-5477-01A-01R-1635-07
lung-landscapes@6
cohortSQ20.786
6MDT-AP-3297
medullo-epn-umap@date-based
MedMedulloblastoma0.784
7MDT-AP-0167
medullo-epn-umap@date-based
MedMedulloblastoma0.781
8s0094236
melanoma-umap@29
0.777
9D38D3FD9-7A58-43D0-876C-6235DA833043
brain-umap@2
0.777
10431CF176-101C-482F-B2A4-617ADF6475A8
brain-umap@2
0.774