Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

20030061.LumA

· A

8c2750ee-d234-5069-895a-e2833e384d8f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
A
subtype
A

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • UV_RESPONSE_DN+0.360
  • TGF_BETA_SIGNALING+0.220
  • ALLOGRAFT_REJECTION+0.180
  • IL2_STAT5_SIGNALING+0.160
  • IL6_JAK_STAT3_SIGNALING+0.150
  • KRAS_SIGNALING_UP+0.120
  • WNT_BETA_CATENIN_SIGNALING+0.110
  • PROTEIN_SECRETION+0.100
  • INFLAMMATORY_RESPONSE+0.050
  • INTERFERON_GAMMA_RESPONSE+0.040

Top 10 suppressed

  • E2F_TARGETS-0.650
  • MYC_TARGETS_V2-0.630
  • MYC_TARGETS_V1-0.570
  • G2M_CHECKPOINT-0.550
  • MTORC1_SIGNALING-0.520
  • CHOLESTEROL_HOMEOSTASIS-0.430
  • OXIDATIVE_PHOSPHORYLATION-0.430
  • GLYCOLYSIS-0.370
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.360
  • ADIPOGENESIS-0.320

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1AUR-AFUM-TTP1-A-1-0-R-A741-41
breast-umap@18
D0.911
220020052.LumA
breast-umap@18
A0.904
3SRR8518276
breast-umap@18
A0.896
4s0122234
melanoma-umap@29
0.888
5AUR-AER4-TTP1-A-1-0-R-A741-41
breast-umap@18
D0.880
6MBCProject_5856_T0B_RNA
breast-umap@18
A0.874
7TCGA-E2-A15I-01A-21R-A137-07
breast-umap@18
B0.862
8TCGA-AO-A0JG-01A-31R-A084-07
breast-umap@18
A0.851
9TCGA-44-5645-01A-01R-1628-07
lung-landscapes@6
cohortA10.851
10SRR1313099
breast-umap@18
A0.849