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MDT-AP-3068

Med · Medulloblastoma

ccd37927-ce12-5ca0-9aab-fb87d75e2a11

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
age_years
31.5
sex
M
new_clusters
S1
umap1_2d
-0.060918296
umap2_2d
-11.75104728
umap1_3d
-2.487088681
umap2_3d
0.316472489
umap3_3d
5.595002995
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • COAGULATION+0.140
  • BILE_ACID_METABOLISM+0.130
  • PANCREAS_BETA_CELLS+0.080
  • KRAS_SIGNALING_DN+0.050
  • UV_RESPONSE_DN+0.050
  • KRAS_SIGNALING_UP+0.040
  • PROTEIN_SECRETION+0.040
  • APOPTOSIS-0.010
  • HEDGEHOG_SIGNALING-0.010
  • P53_PATHWAY-0.030

Top 10 suppressed

  • G2M_CHECKPOINT-0.470
  • E2F_TARGETS-0.450
  • MTORC1_SIGNALING-0.430
  • CHOLESTEROL_HOMEOSTASIS-0.320
  • MYC_TARGETS_V2-0.320
  • GLYCOLYSIS-0.310
  • UNFOLDED_PROTEIN_RESPONSE-0.300
  • DNA_REPAIR-0.290
  • PI3K_AKT_MTOR_SIGNALING-0.270
  • IL6_JAK_STAT3_SIGNALING-0.250

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-3086
medullo-epn-umap@date-based
MedMedulloblastoma0.900
2SRR13311172
bladder-landscape@3
0.886
3SRR1516040
bladder-landscape@3
0.883
4SRR8518163
breast-umap@18
A0.873
5C3N-02950
lung-landscapes@6
cohortA10.872
6TCGA-44-6148-01A-11R-1755-07
lung-landscapes@6
cohortA10.871
7SRR8942979
bladder-landscape@3
0.868
8TCGA-55-A4DG-01A-11R-A24H-07
lung-landscapes@6
cohortA10.866
9SRR6013517
lung-landscapes@6
cohortA10.863
10b03ebc32.a177.44c7.8b02.fcd6560712f2
lung-landscapes@6
cohortA10.862