BS_QV51J756

Ganglioglioma

e4acd5ea-c873-5960-a893-99a85e58ce75

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type: Ganglioglioma
cancer_type_detailed: —
subtype: —
cancer_type: Ganglioglioma
overall_survival_months: 17.608409986859396
age_years: 9.512
sex: Male

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

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Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

3 twins match this tumor's tissue · 7 come from a different tissue of origin ← cross-tissue dominant

#	Sample	Cancer type	Subtype	cos similarity
1	BS_ZR96A4FH brain-umap@2	DNET	—	0.986
2	BS_C7N3J4NW brain-umap@2	high-grade glioma	—	0.965
3	BS_6MY8W3H0 brain-umap@2	DNET	—	0.964
4	BS_7B89YR6K medullo-epn-umap@date-based	EPN	Posterior Fossa EPN	0.963
5	BS_92VDQ0NE brain-umap@2	Ganglioglioma	—	0.962
6	BS_KPT2WPHW brain-umap@2	Ganglioglioma	—	0.961
7	BS_7B89YR6K brain-umap@2	Posterior Fossa Ependymoma	—	0.960
8	SRR1472323 brain-umap@2	GTEX	—	0.957
9	BS_K5802F84 brain-umap@2	pilocytic astrocytoma	—	0.955
10	BS_QF5VVZX5 brain-umap@2	Ganglioglioma	—	0.950

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 14 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)	tumor score	Best drug	reversal magnitude
KRAS_SIGNALING_DN	0.460	Remibrutinib	— uncovered
PANCREAS_BETA_CELLS	0.350	Cobimetinib	— uncovered
APICAL_SURFACE	0.317	Temsirolimus	— uncovered
MYOGENESIS	0.307	Inavolisib	— uncovered
HEDGEHOG_SIGNALING	0.261	Inavolisib	— uncovered
SPERMATOGENESIS	0.221	Inavolisib	— uncovered
BILE_ACID_METABOLISM	0.166	Inavolisib	— uncovered
ESTROGEN_RESPONSE_EARLY	0.158	Inavolisib	— uncovered
ESTROGEN_RESPONSE_LATE	0.153	Idelalisib	— uncovered
COAGULATION	0.121	Binimetinib	— uncovered
XENOBIOTIC_METABOLISM	0.112	Inavolisib	— uncovered
APICAL_JUNCTION	0.082	Inavolisib	— uncovered
KRAS_SIGNALING_UP	0.057	Inavolisib	— uncovered
INFLAMMATORY_RESPONSE	0.004	Idelalisib	— uncovered