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SRR1375952

GTEX

fe2a0350-5cd2-5acb-ab89-b28437b3f1e7

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
GTEX
cancer_type_detailed
subtype
cancer_type
GTEX
sex
Male

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR665670
brain-umap@2
GTEX0.873
2SRR1329835
brain-umap@2
GTEX0.873
3SRR1362777
brain-umap@2
GTEX0.867
4SRR1355373
brain-umap@2
GTEX0.865
5SRR1470212
brain-umap@2
GTEX0.862
6SRR1396659
brain-umap@2
GTEX0.858
7SRR608598
brain-umap@2
GTEX0.858
8SRR1329551
brain-umap@2
GTEX0.856
9SRR1470035
brain-umap@2
GTEX0.855
10SRR1430248
brain-umap@2
GTEX0.855

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 19 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
INTERFERON_ALPHA_RESPONSE0.503Inavolisib— uncovered
INTERFERON_GAMMA_RESPONSE0.383Idelalisib— uncovered
ALLOGRAFT_REJECTION0.379Idelalisib— uncovered
IL6_JAK_STAT3_SIGNALING0.275Inavolisib— uncovered
INFLAMMATORY_RESPONSE0.266Idelalisib— uncovered
KRAS_SIGNALING_DN0.223Remibrutinib— uncovered
KRAS_SIGNALING_UP0.216Inavolisib— uncovered
BILE_ACID_METABOLISM0.168Inavolisib— uncovered
COAGULATION0.160Binimetinib— uncovered
COMPLEMENT0.146Inavolisib— uncovered
IL2_STAT5_SIGNALING0.121Idelalisib— uncovered
APICAL_SURFACE0.100Temsirolimus— uncovered
EPITHELIAL_MESENCHYMAL_TRANSITION0.085Inavolisib— uncovered
ESTROGEN_RESPONSE_LATE0.070Idelalisib— uncovered
APOPTOSIS0.065Idelalisib— uncovered
MYOGENESIS0.042Inavolisib— uncovered
HEME_METABOLISM0.040Temsirolimus— uncovered
XENOBIOTIC_METABOLISM0.029Inavolisib— uncovered
APICAL_JUNCTION0.006Inavolisib— uncovered