Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG551

26e52488-8d16-5116-bd3f-a4fd0876a024

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PROTEIN_SECRETION+0.423
  • TGF_BETA_SIGNALING+0.322
  • UV_RESPONSE_DN+0.304
  • ANDROGEN_RESPONSE+0.259
  • WNT_BETA_CATENIN_SIGNALING+0.223
  • ALLOGRAFT_REJECTION+0.215
  • UNFOLDED_PROTEIN_RESPONSE+0.214
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.171
  • PEROXISOME+0.161
  • MYC_TARGETS_V1+0.143

Top 10 suppressed

  • CHOLESTEROL_HOMEOSTASIS-0.367
  • TNFA_SIGNALING_VIA_NFKB-0.338
  • PANCREAS_BETA_CELLS-0.304
  • E2F_TARGETS-0.257
  • G2M_CHECKPOINT-0.225
  • ESTROGEN_RESPONSE_LATE-0.215
  • UV_RESPONSE_UP-0.201
  • ESTROGEN_RESPONSE_EARLY-0.185
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.181
  • APICAL_SURFACE-0.159

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG442
mng-umap@100
0.851
2TCGA-44-2665-01A-01R-A278-07
lung-landscapes@6
cohortMD20.725
3MNG997
mng-umap@100
0.718
4MNG430
mng-umap@100
0.697
5MNG396
mng-umap@100
0.695
6MNG633
mng-umap@100
0.695
7MNG642
mng-umap@100
0.680
8MNG310
mng-umap@100
0.677
9R404
bladder-landscape@3
0.675
10MNG525
mng-umap@100
0.673