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TCGA-18-4086-01A-01R-1100-07

· cohortSQ2

53b87573-427a-55db-8259-4bf45d38f4e4

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
cohortSQ2
subtype
cohortSQ2
age_years
64

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V1+0.600
  • E2F_TARGETS+0.550
  • OXIDATIVE_PHOSPHORYLATION+0.480
  • MTORC1_SIGNALING+0.460
  • G2M_CHECKPOINT+0.450
  • REACTIVE_OXYGEN_SPECIES_PATHWAY+0.440
  • MYC_TARGETS_V2+0.430
  • DNA_REPAIR+0.360
  • UNFOLDED_PROTEIN_RESPONSE+0.280
  • PI3K_AKT_MTOR_SIGNALING+0.260

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.280
  • ANGIOGENESIS-0.170
  • NOTCH_SIGNALING-0.170
  • COAGULATION-0.130
  • INTERFERON_GAMMA_RESPONSE-0.100
  • KRAS_SIGNALING_UP-0.070
  • WNT_BETA_CATENIN_SIGNALING-0.070
  • ESTROGEN_RESPONSE_EARLY-0.030
  • MYOGENESIS-0.030
  • BILE_ACID_METABOLISM-0.010

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-0322
medullo-epn-umap@date-based
MedMedulloblastoma0.872
2TCGA-22-5473-01A-01R-1635-07
lung-landscapes@6
cohortSQ20.847
3TCGA-18-3411-01A-01R-0980-07
lung-landscapes@6
cohortSQ20.837
4SRR12696742
melanoma-umap@29
0.835
5TCGA-66-2759-01A-01R-0851-07
lung-landscapes@6
cohortSQ20.833
6TCGA-66-2727-01A-01R-0980-07
lung-landscapes@6
cohortSQ20.833
7TCGA-66-2783-01A-01R-1201-07
lung-landscapes@6
cohortSQ20.829
8TCGA-46-3765-01A-01R-0980-07
lung-landscapes@6
cohortSQ20.828
9SRR23303771
bladder-landscape@3
0.827
10TCGA-60-2723-01A-01R-0851-07
lung-landscapes@6
cohortSQ20.823