Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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0b5850f2-648a-4dad-a48d-82150c12acb4

7049412f-1a02-59d2-a091-619fd97ec26f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V2+0.100
  • PANCREAS_BETA_CELLS+0.100
  • BILE_ACID_METABOLISM+0.000
  • KRAS_SIGNALING_DN+0.000
  • MYC_TARGETS_V1+0.000
  • ANDROGEN_RESPONSE-0.100
  • HEME_METABOLISM-0.100
  • IL6_JAK_STAT3_SIGNALING-0.100
  • KRAS_SIGNALING_UP-0.100
  • P53_PATHWAY-0.100

Top 10 suppressed

  • E2F_TARGETS-0.500
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.500
  • TGF_BETA_SIGNALING-0.500
  • CHOLESTEROL_HOMEOSTASIS-0.400
  • G2M_CHECKPOINT-0.400
  • HEDGEHOG_SIGNALING-0.400
  • PROTEIN_SECRETION-0.400
  • ANGIOGENESIS-0.300
  • APICAL_JUNCTION-0.300
  • COMPLEMENT-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1sclc265549_S73.txt
lung-landscapes@6
cohortMD10.890
2SRR650197
bladder-landscape@3
0.870
3aMVAC.P_005_TURBT_S223
bladder-landscape@3
0.870
4SRR23303775
bladder-landscape@3
0.865
5SRR8943010
bladder-landscape@3
0.864
6SRR13311179
bladder-landscape@3
0.856
7SRR8943017
bladder-landscape@3
0.856
8TCGA-CF-A27C-01A-11R-A16R-07
bladder-landscape@3
0.854
9TCGA-E7-A3Y1-01A-11R-A22U-07
bladder-landscape@3
0.853
10SRR1516072
bladder-landscape@3
0.851