b8135e73-31c3-49af-b4da-a7ed5f28d68a
—
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- —
- cancer_type_detailed
- —
- subtype
- —
- age_years
- 62
GSVA pathway preview (0 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
7 twins match this tumor's tissue · 3 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | 62454053-936d-4f19-8522-6219c47bdd1c | — | — | 0.985 |
| 2 | d1447a31-64bb-4e70-ae50-eeff7a605f38 | — | — | 0.976 |
| 3 | TCGA-A7-A0DB-01C-02R-A277-07 | — | D | 0.971 |
| 4 | e356598b-7611-492a-98ed-ef2ec1b77b7a | — | — | 0.968 |
| 5 | 69550f7f-5251-4657-863b-bd35d69c82c4 | — | — | 0.967 |
| 6 | ed8896f8-24ef-43a4-ace6-ed9353bd11c2 | — | — | 0.962 |
| 7 | SRR627429 | GTEX | — | 0.941 |
| 8 | SRR627455 | GTEX | — | 0.938 |
| 9 | SRR627462 | GTEX | — | 0.932 |
| 10 | TCGA-A7-A13D-01B-04R-A277-07 | — | D | 0.931 |
Per-pathway drug coverage
For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.
0 of 5 elevated pathways have at least one drug that meaningfully reverses them.
| Pathway (elevated) | tumor score | Best drug | reversal magnitude |
|---|---|---|---|
| UV_RESPONSE_DN | 0.350 | Inavolisib | — uncovered |
| SPERMATOGENESIS | 0.240 | Inavolisib | — uncovered |
| PROTEIN_SECRETION | 0.080 | Remibrutinib | — uncovered |
| MITOTIC_SPINDLE | 0.040 | Inavolisib | — uncovered |
| KRAS_SIGNALING_DN | 0.020 | Remibrutinib | — uncovered |