Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
Sign in

ERR2598238

fetal · fetal

e14211f4-39ae-5947-bd1c-f1823021fa15

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
fetal
cancer_type_detailed
subtype
fetal
cancer_type
fetal
subtype
fetal
sex
fetal
race
fetal
fetal_age_hindbrain
8
umap1_2d
-4.321041008
umap2_2d
3.324340532
umap1_3d
-2.502554142
umap2_3d
2.887837582
umap3_3d
-1.311858839
dataset
fetal

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MYC_TARGETS_V1+0.500
  • G2M_CHECKPOINT+0.420
  • E2F_TARGETS+0.410
  • MITOTIC_SPINDLE+0.390
  • WNT_BETA_CATENIN_SIGNALING+0.380
  • NOTCH_SIGNALING+0.360
  • HEDGEHOG_SIGNALING+0.350
  • DNA_REPAIR+0.340
  • OXIDATIVE_PHOSPHORYLATION+0.270
  • MTORC1_SIGNALING+0.220

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.560
  • IL6_JAK_STAT3_SIGNALING-0.500
  • INFLAMMATORY_RESPONSE-0.500
  • INTERFERON_GAMMA_RESPONSE-0.490
  • ALLOGRAFT_REJECTION-0.460
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.440
  • COMPLEMENT-0.430
  • COAGULATION-0.410
  • IL2_STAT5_SIGNALING-0.380
  • TNFA_SIGNALING_VIA_NFKB-0.360

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1ERR2598229
medullo-epn-umap@date-based
fetalfetal0.971
2ERR2598195
medullo-epn-umap@date-based
fetalfetal0.945
3ERR2598206
medullo-epn-umap@date-based
fetalfetal0.945
4ERR2598212
medullo-epn-umap@date-based
fetalfetal0.935
5ERR2598235
medullo-epn-umap@date-based
fetalfetal0.929
6MDT-AP-0432
medullo-epn-umap@date-based
MedMedulloblastoma0.911
7BS_1EN5V3XW
brain-umap@2
high-grade glioma0.906
8ERR2598198
medullo-epn-umap@date-based
fetalfetal0.906
97DC6D598-8506-4680-81DF-C1D0F1B5C27D
brain-umap@2
0.901
10ERR2598196
medullo-epn-umap@date-based
fetalfetal0.898