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MDT-AP-2628

Med · Medulloblastoma

e14643a6-3e2a-5360-9d51-b3a4ba147ef0

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
overall_survival_months
8.040000000000001
os_event
false
age_years
11
sex
M
new_clusters
C5
umap1_2d
5.608960269
umap2_2d
4.912295703
umap1_3d
2.031812442
umap2_3d
-0.39342571
umap3_3d
-1.589213308
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PANCREAS_BETA_CELLS+0.360
  • XENOBIOTIC_METABOLISM+0.310
  • KRAS_SIGNALING_DN+0.290
  • ESTROGEN_RESPONSE_LATE+0.270
  • COAGULATION+0.230
  • IL6_JAK_STAT3_SIGNALING+0.180
  • ALLOGRAFT_REJECTION+0.160
  • INFLAMMATORY_RESPONSE+0.160
  • MYOGENESIS+0.160
  • SPERMATOGENESIS+0.160

Top 10 suppressed

  • MYC_TARGETS_V2-0.470
  • UNFOLDED_PROTEIN_RESPONSE-0.410
  • ANDROGEN_RESPONSE-0.380
  • MYC_TARGETS_V1-0.380
  • MITOTIC_SPINDLE-0.360
  • G2M_CHECKPOINT-0.340
  • TGF_BETA_SIGNALING-0.340
  • UV_RESPONSE_DN-0.320
  • PROTEIN_SECRETION-0.310
  • NOTCH_SIGNALING-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

5 twins match this tumor's tissue · 5 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1MDT-AP-0572
medullo-epn-umap@date-based
MedMedulloblastoma0.849
2MDT-AP-2120
medullo-epn-umap@date-based
MedMedulloblastoma0.845
3SRR5088872
melanoma-umap@29
0.829
4ERR2598288
medullo-epn-umap@date-based
fetalfetal0.826
5MDT-AP-2579
medullo-epn-umap@date-based
MedMedulloblastoma0.823
6ERR2598335
medullo-epn-umap@date-based
fetalfetal0.818
7ERR2598269
medullo-epn-umap@date-based
fetalfetal0.814
8SRR1443895
brain-umap@2
GTEX0.813
9MDT-AP-0720
medullo-epn-umap@date-based
MedMedulloblastoma0.810
10SJEPD006_D.RNA-Seq
medullo-epn-umap@date-based
EPNSupratentorial EPN0.810