Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PROTEIN_SECRETION+0.300
  • G2M_CHECKPOINT+0.100
  • MYC_TARGETS_V2+0.100
  • SPERMATOGENESIS+0.100
  • UV_RESPONSE_DN+0.100
  • ANDROGEN_RESPONSE+0.000
  • BILE_ACID_METABOLISM+0.000
  • HEDGEHOG_SIGNALING+0.000
  • KRAS_SIGNALING_DN+0.000
  • PANCREAS_BETA_CELLS+0.000

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.500
  • INTERFERON_GAMMA_RESPONSE-0.500
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.500
  • ADIPOGENESIS-0.400
  • COMPLEMENT-0.400
  • IL6_JAK_STAT3_SIGNALING-0.400
  • INFLAMMATORY_RESPONSE-0.400
  • TNFA_SIGNALING_VIA_NFKB-0.400
  • ALLOGRAFT_REJECTION-0.300
  • ANGIOGENESIS-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

5 twins match this tumor's tissue · 5 come from a different tissue of origin ← cross-tissue dominant

#SampleCancer typeSubtypecos similarity
1SAMN03290913
melanoma-umap@29
0.881
2SRR1317808
brain-umap@2
GTEX0.880
3SRR627451
brain-umap@2
GTEX0.878
4SRR1434782
brain-umap@2
GTEX0.874
5TCGA-A7-A0DC-01A-11R-A00Z-07
breast-umap@18
D0.873
6MNG45
mng-umap@100
0.872
7s_150324_3b
medullo-epn-umap@date-based
EPNPosterior Fossa EPN0.870
8SRR8613756
breast-umap@18
E0.870
9SRR657997
brain-umap@2
GTEX0.867
10a277c487-2d13-460f-a0d8-26acac1657d0
melanoma-umap@29
0.866