Variant atlas
200 annotated variants across the profiled kinome. Each entry links to drug activity on-variant vs. wild-type.
116
Point
40
Compound
20
Indel
20
Fusion
4
Unknown
ALK (T1151-L1152insT)
indelp.T1151-L1152insT
BRAF (R506_K507insVLR)
indelp.R506_K507insVLR
BRAF (T599_V600insT)
indelp.T599_V600insT
EGFR (A763_Y764insFHEA)
indelp.A763_Y764insFHEA
EGFR (A763_Y764insFQEA)
indelp.A763_Y764insFQEA
EGFR (A767_S768insTLA)
indelp.A767_S768insTLA
EGFR (D770_N771insG)
indelp.D770_N771insG
EGFR (D770_N771insNPG)
indelp.D770_N771insNPG
EGFR (N771_P772insH)
indelp.N771_P772insH
EGFR (N771_P772insN)
indelp.N771_P772insN
EGFR (V769_D770insGE)
indelp.V769_D770insGE
EGFR (d747-749)
indelp.747_749del
ERBB2 (A775_G776insYVMA)
indelp.A775_G776insYVMA
ERBB2 (P780_Y781insGSP)
indelp.P780_Y781insGSP
ERBB2 (V777_G778insCG)
indelp.V777_G778insCG
FLT3 (F594_R595insR)
indelp.F594_R595insR
FLT3 (F594_R595insREY)
indelp.F594_R595insREY
FLT3 (ITD)
indelp.internal tandem duplication aa591-601
FLT3 (R595_E596insEY)
indelp.R595_E596insEY
FLT3 (Y591_V592insVDFREYEYD)
indelp.Y591_V592insVDFREYEYD