CAMK1G(CAMK1g)
Sign in to save this workspaceUniProt Q96NX5 · PDB · AlphaFold · Substrate: Autocamtide 2 + Ca-CaM · Clone: C-terminal truncation
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|---|---|---|---|---|
| 1 | Sunitinib | 65.6% | 34.4% | 91.73 | 0.524 |
| 2 | Dabrafenib | 51.7% | 48.3% | 94.74 | 0.633 |
| 3 | Neratinib | 41.1% | 58.9% | 93.18 | 0.597 |
| 4 | Abemaciclib | 38.3% | 61.7% | 91.48 | 0.563 |
| 5 | Bosutinib | 38.2% | 61.8% | 87.22 | 0.555 |
| 6 | Nintedanib | 29.6% | 70.4% | 90.23 | 0.608 |
| 7 | Abrocitinib | 28.1% | 71.9% | 99.50 | 0.581 |
| 8 | Rabusertib | 26.2% | 73.8% | 98.74 | 0.687 |
| 9 | Pacritinib | 23.6% | 76.4% | 88.64 | 0.452 |
| 10 | Tepotinib | 23.4% | 76.6% | 99.75 | 0.727 |
| 11 | Infigratinib | 20.4% | 79.6% | 98.24 | 0.710 |
| 12 | Paxalisib | 17.8% | 82.3% | 99.75 | 0.609 |
| 13 | Ripretinib | 15.9% | 84.1% | 92.95 | 0.674 |
| 14 | Baricitinib | 14.5% | 85.5% | 97.99 | 0.616 |
| 15 | Pazopanib | 14.1% | 85.9% | 97.49 | 0.672 |
| 16 | Ponatinib | 11.9% | 88.1% | 78.23 | 0.534 |
| 17 | Mitapivat | 11.8% | 88.2% | 100.00 | 0.625 |
| 18 | Leniolisib | 11.2% | 88.8% | 100.00 | 0.604 |
| 19 | Sirolimus | 10.5% | 89.5% | 100.00 | 0.708 |
| 20 | Lorlatinib | 10.5% | 89.5% | 97.24 | 0.694 |
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 0.56
- Epithelial log2(TPM+1): 0.09
- Fold change: 0.46
- Status: No significant change
Selectivity landscape vs inhibition on CAMK1G
Each point is one of the 92 approved drugs; color = inhibition % on CAMK1G.
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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