Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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MNG516

02958b30-3c07-5b47-a1cd-2e23843064f9

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • DNA_REPAIR+0.248
  • ALLOGRAFT_REJECTION+0.143
  • INTERFERON_GAMMA_RESPONSE+0.139
  • INTERFERON_ALPHA_RESPONSE+0.100
  • PEROXISOME+0.065
  • PI3K_AKT_MTOR_SIGNALING+0.056
  • FATTY_ACID_METABOLISM-0.034
  • TGF_BETA_SIGNALING-0.037
  • IL6_JAK_STAT3_SIGNALING-0.052
  • MITOTIC_SPINDLE-0.054

Top 10 suppressed

  • ANGIOGENESIS-0.483
  • ESTROGEN_RESPONSE_EARLY-0.383
  • ESTROGEN_RESPONSE_LATE-0.360
  • HEDGEHOG_SIGNALING-0.349
  • ANDROGEN_RESPONSE-0.345
  • APICAL_SURFACE-0.335
  • MTORC1_SIGNALING-0.335
  • EPITHELIAL_MESENCHYMAL_TRANSITION-0.324
  • COAGULATION-0.323
  • COMPLEMENT-0.302

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MNG53
mng-umap@100
0.855
2TCGA-ZF-A9R5-01A-12R-A42T-07
bladder-landscape@3
0.805
3MNG881
mng-umap@100
0.804
4MNG1271
mng-umap@100
0.795
5AUR-AF9A-TTP1-A-1-0-R-A741-41
breast-umap@18
D0.792
6MNG876
mng-umap@100
0.791
7MNG1037
mng-umap@100
0.783
8SRR1313096
breast-umap@18
B0.782
9MNG73
mng-umap@100
0.776
10SRR650134
bladder-landscape@3
0.775