Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR1338323

GTEX

08e371ca-4711-58c3-92f8-38c8862ead46

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
GTEX
cancer_type_detailed
subtype
cancer_type
GTEX
sex
Female

GSVA pathway preview (0 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

No GSVA scores available for this sample.

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR1402513
brain-umap@2
GTEX0.988
2SRR1486741
brain-umap@2
GTEX0.987
3SRR1429935
brain-umap@2
GTEX0.987
4SRR1439850
brain-umap@2
GTEX0.986
5SRR1465132
brain-umap@2
GTEX0.983
6SRR1338669
brain-umap@2
GTEX0.982
7SRR1419675
brain-umap@2
GTEX0.981
8SRR1331841
brain-umap@2
GTEX0.981
9SRR1441200
brain-umap@2
GTEX0.981
10SRR1384234
brain-umap@2
GTEX0.980

Per-pathway drug coverage

ModeledCalibratedDerived

For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.

0 of 3 elevated pathways have at least one drug that meaningfully reverses them.

Pathway (elevated)tumor scoreBest drugreversal magnitude
DNA_REPAIR0.118Idelalisib— uncovered
KRAS_SIGNALING_DN0.109Remibrutinib— uncovered
SPERMATOGENESIS0.049Inavolisib— uncovered