MDT-AP-3273
Med · Medulloblastoma
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- Med
- cancer_type_detailed
- —
- subtype
- Medulloblastoma
- cancer_type
- Med
- subtype
- Medulloblastoma
- age_years
- 30.5
- sex
- F
- new_clusters
- S1
- umap1_2d
- 0.124363517
- umap2_2d
- -11.69270266
- umap1_3d
- -2.626199568
- umap2_3d
- 0.311166772
- umap3_3d
- 6.253301026
- dataset
- Med-Taylor
GSVA pathway preview (50 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Top 10 elevated
- MYC_TARGETS_V2+0.260
- MITOTIC_SPINDLE+0.230
- PROTEIN_SECRETION+0.150
- E2F_TARGETS+0.120
- MYC_TARGETS_V1+0.080
- ANDROGEN_RESPONSE+0.060
- NOTCH_SIGNALING+0.060
- BILE_ACID_METABOLISM+0.040
- PEROXISOME+0.040
- UV_RESPONSE_DN+0.020
Top 10 suppressed
- TNFA_SIGNALING_VIA_NFKB-0.410
- UV_RESPONSE_UP-0.410
- REACTIVE_OXYGEN_SPECIES_PATHWAY-0.390
- IL6_JAK_STAT3_SIGNALING-0.380
- ALLOGRAFT_REJECTION-0.370
- EPITHELIAL_MESENCHYMAL_TRANSITION-0.370
- INFLAMMATORY_RESPONSE-0.350
- INTERFERON_ALPHA_RESPONSE-0.350
- P53_PATHWAY-0.330
- INTERFERON_GAMMA_RESPONSE-0.320
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
8 twins match this tumor's tissue · 2 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | bbba6e8b-9e37-45e0-b663-f81631e76828 | — | — | 0.878 |
| 2 | MNG45 | — | — | 0.865 |
| 3 | SJEPD031175_D1.RNA-Seq | EPN | Posterior Fossa EPN | 0.863 |
| 4 | 50d87a6b-8e96-4964-9f23-53cc48c7d9ff | — | — | 0.858 |
| 5 | b98a06c6-3b43-4749-98cf-b28f4ba06845 | — | — | 0.856 |
| 6 | MDT-AP-3265 | Med | Medulloblastoma | 0.855 |
| 7 | SRR650167 | — | — | 0.842 |
| 8 | s_150324_3b | EPN | Posterior Fossa EPN | 0.842 |
| 9 | SRR650132 | — | — | 0.841 |
| 10 | TCGA-A7-A0DC-01A-11R-A00Z-07 | — | D | 0.841 |