Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR1516088

6e9191a4-ff68-56cf-8ba7-f3e88b347650

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
sex
Male

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • TGF_BETA_SIGNALING+0.420
  • WNT_BETA_CATENIN_SIGNALING+0.350
  • UV_RESPONSE_DN+0.210
  • OXIDATIVE_PHOSPHORYLATION+0.130
  • HEME_METABOLISM+0.050
  • INTERFERON_ALPHA_RESPONSE+0.050
  • PROTEIN_SECRETION+0.050
  • APICAL_JUNCTION+0.020
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.050
  • BILE_ACID_METABOLISM-0.060

Top 10 suppressed

  • E2F_TARGETS-0.630
  • G2M_CHECKPOINT-0.490
  • MTORC1_SIGNALING-0.490
  • ALLOGRAFT_REJECTION-0.430
  • INFLAMMATORY_RESPONSE-0.410
  • IL6_JAK_STAT3_SIGNALING-0.400
  • ANGIOGENESIS-0.390
  • MYC_TARGETS_V2-0.380
  • TNFA_SIGNALING_VIA_NFKB-0.370
  • SPERMATOGENESIS-0.360

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR12202454
bladder-landscape@3
0.899
2SRR1516060
bladder-landscape@3
0.837
3SRR8942980
bladder-landscape@3
0.832
4TCGA-E7-A6MF-01A-12R-A32O-07
bladder-landscape@3
0.829
5TCGA-78-7167-01A-11R-2066-07
lung-landscapes@6
cohortA20.820
6SRR1516046
bladder-landscape@3
0.820
7TCGA-55-8087-01A-11R-2241-07
lung-landscapes@6
cohortA10.817
8TCGA-B6-A0X7-01A-11R-A10J-07
breast-umap@18
A0.814
9R247
bladder-landscape@3
0.811
10SRR25617883
breast-umap@18
B0.809