Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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Soft Tissue

132 kinases essential in this lineage (DepMap gene-effect score < -0.5).

Where this lineage sits

MeasuredReferenceDerived

Top kinases mutated in this lineage

MeasuredDerived

Distinct mutations whose organ/cancer label maps to Soft Tissue.

Kinase# distinct mutations
C_KIT23
FGFR44
PDGFRA4
AKT13
EGFR3
ALK2
AKT31
BRAF1
C_MET1
FGFR31
PKD2_PRKD21
RET1

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