Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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SRR12202449

6e5d7e2b-d68f-5f63-9ab5-0f79524e86e7

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PANCREAS_BETA_CELLS+0.350
  • OXIDATIVE_PHOSPHORYLATION+0.260
  • TGF_BETA_SIGNALING+0.200
  • PROTEIN_SECRETION+0.100
  • UV_RESPONSE_DN+0.090
  • WNT_BETA_CATENIN_SIGNALING+0.080
  • ADIPOGENESIS+0.030
  • KRAS_SIGNALING_DN+0.020
  • HEME_METABOLISM+0.010
  • P53_PATHWAY-0.050

Top 10 suppressed

  • G2M_CHECKPOINT-0.610
  • E2F_TARGETS-0.590
  • CHOLESTEROL_HOMEOSTASIS-0.490
  • INTERFERON_ALPHA_RESPONSE-0.430
  • MITOTIC_SPINDLE-0.430
  • MTORC1_SIGNALING-0.380
  • ANGIOGENESIS-0.370
  • IL6_JAK_STAT3_SIGNALING-0.370
  • GLYCOLYSIS-0.340
  • INTERFERON_GAMMA_RESPONSE-0.330

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1SRR8943006
bladder-landscape@3
0.869
2TCGA-CF-A5U8-01A-11R-A28M-07
bladder-landscape@3
0.862
3SRR8943008
bladder-landscape@3
0.861
4SRR8942980
bladder-landscape@3
0.857
5SRR8943010
bladder-landscape@3
0.852
6SRR1516063
bladder-landscape@3
0.845
7SRR2016961
head-neck@1
0.845
8TCGA-37-4129-01A-01R-1100-07
lung-landscapes@6
cohortSC0.831
9MNG1181
mng-umap@100
0.828
10SRR1516050
bladder-landscape@3
0.823