Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
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Skin

140 kinases essential in this lineage (DepMap gene-effect score < -0.5).

Where this lineage sits

MeasuredReferenceDerived

Top kinases mutated in this lineage

MeasuredDerived

Distinct mutations whose organ/cancer label maps to Skin.

Kinase# distinct mutations
C_KIT35
BRAF27
EGFR12
AKT18
FGFR35
AKT34
ABL12
ALK2
FGFR22
AKT21
AXL1
JAK21

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